I am sure everyone who is a fan of Harry Potter is also excited by the marauder's map. Harry uses it to find that Peter Pettigrew is alive and roaming within Hogwarts. Later he also uses it to track Draco. How interesting it must be to have such a map! You can map out what your boss is doing, can monitor where your kid is, etc etc. How wonderful it would be if it were true! Alas, indeed it is now a reality, and no fiction! Thanks to the smartphones and google lattitude/maps! One can enable GPS tracking in one's mobile phone and google map automatically updates your position! Even as one is travelling, you can.know which road he is in and if traffic information is available, one can esotimate time of arrival! On retrospection, the old fantasies and so-called magic are becoming a reality. I don't know if these would have been a reality without the yester years' fantasies and wild imaginations. The only uneasy thing about the old fantasy stories is that, people tend to believe that they are true and people of the past really did have those abilities and facilities. Truly, the stories of those days were born out of curiosity and imaginations. Again, curious people these days b
capitalise on science and technology to bring those imaginations a reality. Cheers to creativity and imaginations!
Friday, July 23, 2010
The Marauder's Map
Thursday, July 22, 2010
Doctrate of Medicine and Neurology
Any higher degree that involves research (particularly, a supervisor) is not an easy job. To complicate it, imagine you have to deal with several people as well. If the people you have to deal with are ill, chronically, and you are deemed to cure them, and at the same time take data for your research. To talk of it is itself head-swiveling for me! And what, my sister has borne all these difficulties and passed her DM Neurology course after a streneous focussed effort of five years. The scholarliness gets infused into your blood only after a great struggle. Salute to the Doctors community who withstand all difficulties and live their dreams to serve people.
One can synchronize your google calendar with your microsoft outlook calendar (click here). So, when using calendar in android phones, I don't have to re-enter my appointments in my google calendar. The sync application automatically does that for me. What more, you can control the information flowing path! You can either choose to update your google calendar with your outlook data, or update outlook data with google calendar, or both ways! Isn't that cool and very useful? But coming to think of it, is Google trying to monopolize? ah...never mind...it is useful, so it is ok. We cannot abandon PC for google, atleast now.

(The photo was taken from a Hindu article )
One can see the four streets around the meenakshi amman temple. It is for this 'whorl' type arrangement, the city has been conventionally called to have the arrangement of a lotus flower.
The scene would be amazing when you look at it in the night with all the lightings! Take an evening flight from madurai to chennai or bangalore to see this panaromic view! ;-)
Tuesday, July 20, 2010
"Talent is just the starting point" somebody said. Yes, it is truly just the starting point. Perseverence and self confidence are the key ingredients to bring a dream to reality. After about two years, my friend's comic has been selected to be one of the best in a comics contest. No doubt his comic story was original, creative and all good adjectives fitted appropriately for his creativity. But it did not gain the immediate reputation he had hoped for. He persevered. Made several attempts to take it to the people in several different ways. And Voila! Finally it got the recognition it deserved. Never give up your dreams!
Monday, July 19, 2010
Perhaps he forwarded it to me to indicate/prick/poke me that I have, of late, not been spending quality time as I was drenched in my own apprehensions, anxieties, confusions, aspirations and commitments, slowly letting go the dose of reality and entering a monotonous melodramatic drama.
There's always room for a couple of cups of coffee with a friend...and so did this saga start at Starbucks. This has been the second time we ventured into such planned unplanned trips. Since it was quite a long time since we met (almost about a year and half), the time was mostly spent on talking talking talking that morning and in the days to continue. Each updating the other of the lived and un-lived moments. For some reason, you get to talk more in person rather than by emails or even phone calls. That makes me wonder what it is that the physical presence does - any quantum entanglement phenomena triggered a cascade event?! Since I had saved time by executing an idiosyncratic plan well-ahead, we had more time that morning. It was then decided to explore the local delights and the downtown Singapore. However, the trip ahead was well punctuated as a result of the explorative nature of our minds. On the way to the destination was the Haw Par Villa which was not in our schedule...but finding it attractive, couldn't resist getting down - pressing the stop button in the bus as the bus was about leave from the stop. So did time pass by there moving around amids the chinese mythological characters and stories of good against evil. Time, though had started moving slow by then, did not fail in its job to induce hunger. Finally towards vivocity again for lunch at Thai Accent. But Vivocity is not a just another place! It has enough retreat for a gadget freak - my companion - that can last more than a day or two! The first target was Best, exploring 3D Tvs, i-products etc. But my hunger somehow realized it was 3.30 pm and was craving for some food that we had to ditch Best halfway to satiate my hunger at Thai accent. Interesting foods. To top it, the Green Apple juice was just amazing! Alrite, hunger satiated...what next? Return to Best to complete surveying the rest of the shop! And from there we slowly moved on to explore Vivocity and to freeze time within the Canon time machine. The phone pouch, the 3-D pictures, sun-activated T-shirts, Sound T-shirts, the pool on the top of the skypark, nothing was left unexplored. Vivocity was followed by Chinatown - Pagoda street - 3 for 10 dollar shops. Well, who can resist buying things over there? Ended up buying interesting stuffs over there. But all these places, we decided not to rush through since our aim was not to 'see' all places, but 'explore' the places that we go. Well, truly, we didn't quite explicitly come to this agreement, but I guess both of us came to an implicit understanding. However, I did nudge a little to keep moving on for the fear of sticking to just one place. Dinner at Chinatown, followed by a walk aside the Singapore River was refreshing. The beautiful night lightings around clarke quay was something I had noticed, but not enjoyed so far. I have enjoyed the evening walks over there though. At the end of these, we decided to explore Mustafa around 1 am. Mustafa, those who have visited it, will know what it is to shop there. It is an ocean of goodies...a one-stop shop for all your needs. A lot of shopping again here.
One might ask, is this all you did in Singapore? Shop...shop...shop? Well, actually yes, the first day was mostly so...but as somebody said, the joy lies while climbing the mountain than reaching the top as such.
The first day needs to be told in such detail because we couldn't freeze much of the time within our time machine - damn the batteries. However, starting the second day, the time machine - the camera - was in full use. So, no details! :-D {alrite, I am getting lazy}.
The five days ran through every minute. It is indeed true that "There's always room for a couple of cups of coffee with a friend". The trick is to realize and honor it at the appropriate time. The apprehensions of the future will definitely cloud the mind always. But truly, the future is designed by the present. If you want to relish your future, you have to live the present!!
Anyway, here are a few tips for the readers:
1. Don't plan your outings to precise details unless needed (sometimes it is necessary to keep to proper eating schedules, especially if diabetic.)
2. Be a tourist who goes and explores the place, rather than knowing what to do in a place apriori. In doing so, you might miss out some places and some events, but you definitely will explore and relish the places you found by exploring!
3. If it is a short trip, give a vacation to your sleep as well!
Friday, July 16, 2010
Taste of technology
This is a new taste for me. I have always refrained hopping into newer technologies for the fear that I may get too much dependent on it. Also because I always believed in the supremacy of man over machine. But this taste of technology with spica tells me how ignorant I have been. A lot of seemingly impossible and 'magical' phenomena are now real. One is able to manage a huge amount of information in easy and undistractable ways. And the all-in-one nature is quite good. Could follow blogs, could write emails, could check location, could maintain my booklists, wishlists, calendars, tasks etc etc. The main purpose of being connected to home through skype has been missing though! But definitely gives a feeling of connectedness.
All these do not make me additive, but explorative! It does not mean supremacy of machine over man, but man over information! Great going so far! :-)
Thursday, July 15, 2010
Perhaps this is true in all careers. We sweat the small stuff and let go the bigger picture. This adds to one more lesson in my life. A lesson taught by experience, the toughest master. :-)
Saturday, July 03, 2010
Thursday, May 20, 2010
New Scientists picks the best illusions of the year. (Click here)
Illusions, I think, are the best way to study cognition!
Tuesday, May 04, 2010
Specific protein-DNA binding has been thought, so far, to be a two-step process. However, a recent study by Sanchez et al (PNAS, 107:7751-7756. April 27, 2010) show that it may not be always the case. They find an equally probable second route – a route that has more rougher energy landscape. By a series of systematic mutations in the protein, the characterize the energy landscape of the second route – which again involves atleast two intermediates. The overall picture is that, there is an initial transition state ensemble with non-native contacts that drive the system into a kinetic trap. These non-native contacts are slowly rearranged into native-like interactions.
There are two points that are quite interesting:
1. That the second route is significantly probable.
2. To think of additional factors such as DNA bending in such a rough energy landscape is mind boggling!
While this study delineates the pathways to protein –DNA binding, yet another study (Genes and Development, 24:814-826) shows that the *shape* of the DNA minor groove directs binding by the protein FIS, a DNA-bending protein. The results of the study seem to suggest that FIS initially selects DNA targets with *intrinsically* narrow minor grooves and then it compresses the minor groove and bends the DNA. The study re-iterates the idea that the shape of the DNA is more important than its sequence – atleast in the noncoding regions, as shown by an earlier study (Science, Vol 324, 389-392, 2009).
Even as it is becoming clearer that the shape of the DNA is important, I think there is a long way to go in understanding what changes occur in the intrinsic properties of the DNA/protein that eventually modulate the structure.
Sunday, March 14, 2010
Since school days, it has been taught to us that natural selection is the primary reason for the origin of species. Only 'fit' individuals survive in a particular environment. That is, it means that that there are certain characteristics needed for survival in a particular environment. So, if natural selection had played its role well, there can be only one species in a given environment - one species of bacteria, one species of a plant, one species of a spider, one species of a mammal etc. But this doesn't seem to be the case. Often several species cohabit an environment. So, it becomes obvious that natural selection cannot explain the 'origin' of species. This has been a contentious issue among evolutionary biologists since long and a recent study probably has revealed the underlying 'fact'. See the nature article. Or, read this New Scientist article which explains the issue in layman terms. According to this study, the origin of species is a random event. A rare event triggers change and a group of individuals in a particular species become reproductively isolated. These isolated group of individuals then gradually change, adapt by natural selection and form the new species.
I think this completes the theory of evolution. A rare event triggers the formation of a new species. This species then adapts to the environment and forms a new species. It seems like randomness is an important aspect of life! Nothing can be predetermined as some claim.
Saturday, March 13, 2010
சற்று சிந்திப்போமே ஏன் அவர்கள் இந்தியாவிலேயே சாதிக்கவில்லை என்று.
சற்று சிந்திப்போமே ஏன் இந்தியாவிலேயே வசிக்கும் 100 கோடி மக்களில் பெருவாரியானவர் சாதிக்கவில்லை என்று.
அல்லது ஏன் தான் நாம் மற்றவர் நம்மை அடையாளம் காணும் வரை பொருத்து இருக்கிறோம்?
English translation: There are great many number of people today, who cite examples of Indians who have achieved in foreign nations and claim the intelligence of Indians. Let us think why these people did not achieve it in India. Let us think why, of the 100 crore people, there are not many achievers. Or, why do we at all wait until a foreign organization identifies the talent in the Indian talent pool?
Friday, February 12, 2010
Global warming is a serious issue if you are concerned about future generations who will live 100 years down. As the international leaders are trying to set up regulations and reduce the global warming, it is necessary that citizens in under-developed and developing nations be educated on Global Warming and the need to go green. "Carbon footprint" is probably the first terminology to understand in this process.
I came across the following links that I consider to be good in educating about carbon footprints and global warming in general.
http://www.carbonfootprint.com/
http://www.carbonify.com/
Friday, January 08, 2010
Sunday, January 03, 2010
Snowflakes have always evoked a sense of awe owing to their beauty and elegance. Various shapes of snowflakes are used in Christmas cards mainly for an aesthetic value and to denote the winter season. However, it is not common knowledge that snowflakes are always six-sided - hexagonal - owing to water's property. For quite sometime now, I have counted the number of edges of snowflakes appearing in commercial ads...and was always intrigued by the nonconformity to the "six". I was getting into the impression that I was wrong about my knowledge of the hexagonal structure of snowflakes. However a recent correspondence in Nature by Prof. Koop from the Bielefeld University helped me assert that I was indeed correct.
I really appreciate Prof. Koop's effort to bring it to the attention of the media that many of the commercial ads are depicting the snowflakes against the laws of Nature. Even as we celebrate festivals and try to include Nature into our celebrations - or perhaps as sources of inspiration and beauty - let us do it the right way. In my opinion, this is one of the responsibilities of Scientists: ensure that the layman gets to appreciate Nature for its elegance and beauty in the right spirits.
Once he gets to learn the intricacies and complexities of Nature, his appreciation for Science would increase and critical thinking for productivity would be automatically be inculcated.
Saturday, December 19, 2009
I was fortunate to attend a talk on "The search for extra dimensions" by the Indian Physicist Dr. Sayen Kar at IIT Kharagpur. He highlighted that there are numerous experimental observations in Physics that can be explained only if we invoke the presence of extra dimensions (that is apart from the usual x,y,z and time dimensions). However, these dimensions become "visible" only at sub-micron length scales and requires high-energy techniques (like the Large Hadron Collider). I couldn't really imagine the presence of an extra dimension. It was hard convincing myself. However, it struck me that this would have been the state of mind before people discovered microbes! Nobody knew what caused diseases. The invent of microscopes was a milestone in knowing the microscopic world - organisims not visible to the eye. Similarly, I think we need high-end techniques like the LHCs before we really explore and perceive the presence/absence of the extra dimensions. In all cases, nothing can be ruled out until proved otherwise! :-)
I thought quite deeply about the social responsibility of Science when I wrote my previous blogpost (click here). However, I was very skeptical of how much my view was right, though I did get a few feedbacks agreeing to my opinions. A recent article in SciAM "War in Peace" parallels my thoughts. The author very clearly points out "Discerning the merits of competing claims is where the empirical basis of Science should play a role". The competing claims may be in any area. I am indeed happy that I understood this aspect of Science, quite right, thanks to Feynman of course! But the question is, why don't everybody who holds a degree in Science understand this?? Wouldn't the world be a better place if everyone agreed to this aspect? In the same issue of SciAm, Michael Shermer (click here) informs us of a research work in psychology that identifies 5 innate and universally available psychological systems upon which our senses of right and wrong rest. The underlying basis of opinion difference is now delineated!!
Friday, December 18, 2009
Recently, there was much news that Indian scientists were successful in sequencing an Indian genome. It is a great step indeed for India and shows its promise of progress. However, on retrospection, I wonder if this is any news at all! The human genome project published its first sequence around the year 2000. This means, the technology for sequencing was developed even before that...say 5 years (though the actual root is the invention of the PCR in 1983 - even before I was born!). So, this only means that Indians are lagging behind by at least 15 years now!! In addition, I learn from news that the sequencing technology license was bought from an european organization. So, what was so indigenous to India to celebrate the sequencing? Was there any break through data that leapt out - at least as of now, NO - there hasn't been a publication yet! So, why did the government choose to announce it prematurely? I have no clue! There are lot of things to do with sequencing - population genetics of the different races, cause for the malarial susceptibility etc etc etc. Couldn't the scientists have waited until there was good data to publish? I seriously don't understand their motive from a scientific point of view when there is no novelty displayed yet.
Singapore being one of the most "light-polluted" countries, I never thought there would be an astronomical observatory here. But as it happens, there is one...and in fact, one of the few telescopes on the equator! And what more...they offer 'free star gazing' every friday between 7.45 and 10 pm! The planet on focus today was Jupiter - as that was the most observable celestial body today - perhaps the whole of December. There was a big hood like thing..as we see in the movies... in which the telescope was mounted. I guess the whole of the hood was rotatable to view different parts of the sky. The telescopic image showed 4 moons along with the planet. It just made me wonder how much our 'vision' has improved :P (The proposed site for the Indian Neutrino Observatory has been dismissed by the government). There a lot of things that we don't know and are beyond our imagination too. It is so interesting how people live in so much vanity when there are a lot of stuffs that we don't understand and do not even perceive! That apart, I also saw a small satellite that crossed Singapore while I was there...apparently it reflected the sun's light for a fraction of a minute on its way...and was observable at Singapore. One can get a list of observable satellites in their location for the next 7 days from this website: http://www.heavens-above.com/.
Astronomy is fun and humbling!